Editing MAS-GE 1999

{{Infobox chemical
| name = MAS-GE 1999
| chemical_class = Synthetic gestational medium
| compound_type = Multicomponent physiological solution
| formulation = Electrolyte-buffered nutrient medium
| state = Liquid
| recorded_use = [[A-Series]]<br>[[R-Series]]
| developer = [[Richard Rambam]]
| manufacturer = [[Snubable Enterprise]]
| first_recorded = 1999
}}

'''MAS-GE 1999''' (Romanian: ''Mediu amniotic sintetic pentru gestație extracorporală, formula 1999'') was a synthetic gestational medium developed by [[Richard Rambam]] and manufactured by [[Snubable Enterprise]]. It circulated through the incubation chambers used to produce the [[A-Series]] and [[R-Series]].

The medium maintained the liquid environment around a developing clone during accelerated growth. Developmental acceleration came from the engineered cells rather than the fluid. The incubation chambers operated at approximately 37&nbsp;°C while separate physiological systems supported the developing body.<ref name="a-series-gestation"/>

== Development ==

Rambam developed MAS-GE 1999 during the first Snubable human cloning experiments in 1999. These experiments used genetic material collected from [[Alexandru Ionuț]] and formed the basis of the A-Series.<ref name="snubable-origins"/>

The first batches were used in adult-sized incubators constructed with improvised laboratory equipment. Rambam adapted the formulation for the vertical incubation chambers introduced as Snubable Enterprise expanded its production system.

The MAS-GE designation came from the Romanian name of the medium. The number 1999 identified the year in which the formulation entered use.

Snubable Enterprise later standardized its preparation for factory production. On 16 April 2011, the company completed a western annex at its factory complex in [[Căciulați]]. The annex contained equipment for nutrient synthesis and synthetic amniotic fluid preparation.<ref name="factory-expansion"/>

== Composition ==

Purified water formed the base of MAS-GE 1999. Sodium and chloride compounds established its osmotic balance. Potassium supported electrical activity in developing cells. Calcium and magnesium compounds supported muscular and skeletal development.

Bicarbonate and phosphate compounds maintained the required pH. Albumin and synthetic colloids regulated the movement of water between the medium and developing tissue.

Glucose supplied metabolic energy. Amino-acid solutions supported protein synthesis. Lipid emulsions supplied material for the formation of cell membranes.

Vitamins and trace elements were added in low concentrations. Hormone analogues and growth-regulating proteins were adjusted according to the clone's stage of development. Snubable Enterprise restricted the exact concentrations to its biological production personnel.

== Incubation system ==

MAS-GE 1999 formed the liquid environment of the standard Snubable incubation system. A developing clone remained submerged throughout physical maturation. Pumps circulated the medium through a conditioning unit that maintained temperature and corrected changes in pH. Filters removed suspended biological material, and part of the fluid was replaced when filtration could no longer maintain the required conditions.

Early physiological exchange occurred through temporary placenta-like tissue produced from the same reprogrammed source population as the clone. The system changed to direct vascular support after blood flow and cardiac performance reached the required state. Tissue oxygenation provided a further measure of readiness. The change therefore did not occur on a fixed incubation day.<ref name="a-series-gestation"/>

The lungs remained fluid-filled during incubation. The vascular interface oxygenated the blood until removal from the chamber, when lung-fluid clearance and the first breaths began. Neural stimulation operated separately to standardize nervous-system development. Under mature factory conditions, the complete system could produce a physically mature clone in approximately 14 days.<ref name="a-series-gestation"/>

== Use in clone production ==

The A-Series was the first clone line to use MAS-GE 1999. Its clones were produced from cells derived from Alexandru Ionuț and formed the main Snubable production line.<ref name="a-series-basis"/>

The R-Series used the same gestational medium and standard chamber system. Its clones were manufactured from [[Rasmus Rogganoid]] as a private client line. Production ran from 3 September 2011 until 28 November 2012.<ref name="r-series-creation"/>

Genetic identity came from the source material used for each series. MAS-GE 1999 maintained the chamber environment and did not determine the clone's lineage.

== Handling and disposal ==

MAS-GE 1999 was prepared in sealed batches and transferred to the incubation chambers through fixed fluid lines. Production personnel monitored its temperature and pH during each cycle. Electrolyte concentrations were corrected when required.

After extraction of a clone, the remaining medium contained metabolic waste and biological residue. It was removed from the chamber and transferred into the facility waste system. [[Septicsolution]] supported the removal of biological waste from Snubable production areas.<ref name="septicsolution-support"/>

Production of MAS-GE 1999 ended on 1 May 2025 when A-Series production ceased.<ref name="snubable-collapse"/>

== See also ==
* [[A-Series]]
* [[R-Series]]
* [[Snubable Enterprise]]
* [[SPF-2006 Aldehyde Stabilization Fluid]]

== References ==
{{Reflist|refs=
<ref name="snubable-origins">"[[Snubable Enterprise#Formation and early expansion|Formation and early expansion]]". ''Snubable Enterprise''. ''Vrienden Universe Wiki''.</ref>
<ref name="factory-expansion">"[[Snubable Enterprise#Main complex|Main complex]]". ''Snubable Enterprise''. ''Vrienden Universe Wiki''.</ref>
<ref name="a-series-basis">"[[A-Series#Biological basis|Biological basis]]". ''A-Series''. ''Vrienden Universe Wiki''.</ref>
<ref name="a-series-gestation">"[[A-Series#Artificial gestation|Artificial gestation]]". ''A-Series''. ''Vrienden Universe Wiki''.</ref>
<ref name="r-series-creation">"[[R-Series#Creation|Creation]]". ''R-Series''. ''Vrienden Universe Wiki''.</ref>
<ref name="septicsolution-support">"[[Septicsolution#Role in Snubable Enterprise|Role in Snubable Enterprise]]". ''Septicsolution''. ''Vrienden Universe Wiki''.</ref>
<ref name="snubable-collapse">"[[Snubable Enterprise#Collapse|Collapse]]". ''Snubable Enterprise''. ''Vrienden Universe Wiki''.</ref>
}}

[[Category:Snubable Enterprise]]
[[Category:Chemicals]]
[[Category:Biotechnology]]
[[Category:Cloning]]
[[Category:Vriend Era]]